Isotretinoin is safe and efficacious in Asians with acne vulgaris.
J Dermatolog Treat. 2012 Mar 5;
Gan EY, Koh WP, Jin AZ, Tan AW, Tan HH, Tang M
Abstract Background: Oral isotretinoin is effective for acne vulgaris but concerns remain regarding its adverse effects. Objectives: This study aims to evaluate the safety and efficacy of isotretinoin for acne vulgaris in Asian patients. Methods: We conducted a 4-year retrospective study on all patients with acne vulgaris treated with isotretinoin, between January 2005 to December 2008 at the National Skin Centre in Singapore. Medical records were reviewed for information on patient demographics, acne severity, isotretinoin dose, duration, adverse effects and outcome. Results: There were 2,255 patients, with a mean age of 22.5 years, male: female ratio of 2.5:1 and 82.3% being Chinese. The mean starting dose of isotretinoin was 0.4 mg/kg and on average, patients received 7.8 months of treatment at a mean dose of 0.5 mg/kg. Mean total cumulative dose was 95.6 mg/kg. Vast majority (93.9%) achieved complete remission or substantial improvement. Thirty-eight (2.2%) and 24 patients (2.7%) developed elevated serum levels of alanine and aspartate aminotransferases subsequent to treatment. There were 194 (12.1%) and 80 (4.8%) patients who developed hyperlipidaemia and hypertriglyceridaemia respectively. Isotretinoin was generally well-tolerated, with 6.4% (n=145) discontinuing due to side-effects. Conclusions: This study reaffirms the overall safety and efficacy of oral isotretinoin in Asian patients with acne vulgaris.
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@ellurn Id rather have acne than my skin condition(keratosis pilaris on my arms &legs -_-) so crap no shorts/tshirts for me this summer
@ellurn Id rather have acne than my skin condition(keratosis pilaris on my arms &legs -_-) so crap no shorts/tshirts for me this summer
georgiariv@twitter.com (Georgia Burns)
Mon, 12 Mar 2012 16:58:18 +0000
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New Revolutionary Natural Acne Treatment - PRLog (free press release)
In the quest for an acne cure, acne suffers will probably try just about anything to get clear skin. This will involve multiple visits to doctors who will probably prescribe courses of antibiotics, high potent single vitamin supplements, medicated washes …
2012-03-07T12:15:35Z
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Acne-social behaviour: Council considers pink lighting that highlights acne to stop teenage yobs congregating in ASBO …
Cardiff Council wants to install the pink 'spotlight' lamps - usually spotted in the hands of beauticians - to stop teens loitering in the area following a rash of complaints.
Wed, 07 Mar 2012 04:33:42 -0800
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Buy It Now: New Limited Edition Goods From Kid Acne - Complex.com (blog)
Buy It Now: New Limited Edition Goods From Kid Acne
Complex.com (blog)
By Nick Schonberger | Mar 12, 2012 | 8:57 am | Permalink Born in Malawi, Kid Acne lives and works in Sheffield, UK. His teenage years were spent writing graffiti and making underground fanzines. To the naked eye, not much has changed.
Mon, 12 Mar 2012 13:09:50 GMT
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